Created by HANIL SCIENTIFIC
Supporting Exosome research: The Focus of Cutting-Edge Biomedical Research
Cancer, Alzheimer’s, Parkinson’s, and heart diseases remain some of the most complex medical challenges of our time. Exosomes, tiny extracellular vesicles measuring just 30–150 nanometers, are now at the forefront of medical research due to their remarkable ability to diagnose and treat these conditions. Acting as cellular messengers, exosomes carry critical biomolecules that reflect the state of their cells of origin for diagnostics, and have unlimited access within the body, even crossing the blood-brain barrier, offering groundbreaking potential in both diagnostics and therapeutics.
The Golden standard for Exosome isolation***
Ultracentrifugation has long been recognized golden standard for isolating exosomes, setting the benchmark for purity, reliability, and scalability. Its unparalleled ability to separate particles based on size and density ensures the removal of contaminants, delivering highly enriched samples essential for both research and clinical applications.
This method’s precision and reproducibility have made it the cornerstone of exosome isolation, consistently meeting the rigorous demands of scientists and clinicians alike. Despite advancements in alternative techniques, ultracentrifugation remains the gold standard due to its proven track record of delivering consistent, high-quality results across a wide range of biological samples.
For exosome isolation, ultracentrifugation at 100,000 xg is widely regarded as the gold standard, as higher centrifugal forces can potentially damage exosomes and compromise purity by co-isolating other particles. Hanil Scientific offers the Supra R30 and Ultra 5.0 ultracentrifuges, which are well-fit to meet the demands of high-quality and reliable exosome isolation with processing volumes up to 564mL per run. These systems provide an affordable solution compared to other ultracentrifuges on the market, delivering purpose-driven performance that balances efficiency, precision, and affordability. This ensures maximum value without compromising the integrity of your results.
Hanil Scientific’s Ultra 5.0 and Supra R30 centrifuges are well suited to support researchers in separation of exosomes, driving new breakthroughs in biology and medicine. For application guidelines, please contact our sales department.
| Supra R30 | Ultra 5.0 | |
|---|---|---|
| Max. RPM (Fixed angle) | 31,000 rpm | 50,000 rpm |
| Max. RCF (Fixed angle) | 106,258 xg | 254,340 xg |
| Max. capacity (Fixed angle) | 4 x 1,000 mL | 6 x 250 mL |
| ACC / DEC | 10 / 10 steps | 10 / 10 steps |
| Temperature range | -10 °c to 40 °c | -10 °c to 40 °c |
| Time control | < 100 hr, continuous | < 100 hr, continuous |
| Program memory | 100 | 100 |
| Noise level | ≤ 65 dB | ≤ 65 dB |
| Vacuum system | Yes | Yes |
| Rotor identification | Manual | Automatic |
| Dimension (W x D x H, mm) | 710 x 1,000 x 1,260 | 710 x 1,000 x 1,260 |
| Weight without rotor | 415 kg | 450 kg |
| Power consumption | 5.2 kVA | 5.0 kVA |
| Power supply | 210 V ~ 240 V, 60Hz (50 Hz, 110 V optional) | 210 V ~ 240 V, 60Hz (50 Hz, 110 V optional) |
| Cat. No. | SU-R30 | UL-5.0 |